Seminar: Craig J. Goergenhttps://engineering.wustl.edu/Events/Pages/BME-Seminar-Craig-J-Goergen.aspx1611Seminar: Craig J. Goergen2018-11-15T06:00:00Z10:10 amWhitaker Hall Room 218<p>​</p><div style="font-variant-numeric: normal; font-variant-east-asian: normal; background-color: transparent; border-width: 0px; font-family: "open sans", "helvetica neue", helvetica, arial, sans-serif; border-collapse: collapse; border-spacing: 0px;"><span rtenodeid="6"><a href="https://engineering.purdue.edu/cvirl" rtenodeid="4"><strong>Craig J. Goergen, PhD</strong></a><strong>, is an Assistant Professor at Purdue University</strong></span><span style="background-color: transparent;"><strong>, will present.  </strong></span></div><div style="font-variant-numeric: normal; font-variant-east-asian: normal; background-color: transparent; border-width: 0px; font-family: "open sans", "helvetica neue", helvetica, arial, sans-serif; border-collapse: collapse; border-spacing: 0px;"><span style="background-color: transparent;"><strong><br/></strong></span></div><div style="font-variant-numeric: normal; font-variant-east-asian: normal; background-color: transparent; border-width: 0px; font-family: "open sans", "helvetica neue", helvetica, arial, sans-serif; border-collapse: collapse; border-spacing: 0px;"><span style="background-color: transparent;"><strong><em></em></strong></span></div><a href="/Events/Documents/FLYER%20-Craig%20J.%20Goergen,%20Ph.D.%20-%20Nov.%2015.pdf"><div style="font-variant-numeric: normal; font-variant-east-asian: normal; background-color: transparent; border-width: 0px; font-family: "open sans", "helvetica neue", helvetica, arial, sans-serif; border-collapse: collapse; border-spacing: 0px;"><span style="background-color: transparent;"><strong><em>Cardiovascular 4D Ultrasound and Photoacoustic Murine Imaging</em><br/></strong></span></div></a><div style="font-variant-numeric: normal; font-variant-east-asian: normal; background-color: transparent; border-width: 0px; font-family: "open sans", "helvetica neue", helvetica, arial, sans-serif; border-collapse: collapse; border-spacing: 0px;"><span style="background-color: transparent;"><strong><em><br/></em></strong></span></div><div style="font-variant-numeric: normal; font-variant-east-asian: normal; background-color: transparent; border-width: 0px; font-family: "open sans", "helvetica neue", helvetica, arial, sans-serif; border-collapse: collapse; border-spacing: 0px;"><p style="text-align: justify;"><span style="text-decoration: underline;">Abstract:</span> </p><p style="text-align: justify;">Cardiovascular disease is the leading cause of death and disability in the world. Non-invasive imaging has become vital for the detection and monitoring of disease progression, aiding in the development of therapeutics and devices. The research highlighted in this talk describes advancements at the interface of engineering and medicine in order to develop and use multiple imaging modalities to better understand cardiac and vascular disease. For example, conventional ultrasound measurements are commonly based on geometric assumptions from 2D images, often yielding inaccurate results with large variability. Because of this, we have developed a respiratory- and cardiac-gated 3D echocardiography technique to reconstruct ultrasound volumes. We imaged 1) the left ventricles of healthy and infarcted wild-type mice and 2) the abdominal aortas of hyperlipidemic mice with angiotensin II-induced dissecting aneurysms using a position-controlled ultrasound transducer. ECG-gated cine loops at 1000 frames-per-second were acquired at sequential positions and temporally concatenated, generating 4D datasets. Nonlinear image registration was then utilized to calculate deformation fields and project segmented masks across the cardiac cycle and from aneurysmal vessels. The dissecting aneurysm datasets were also used to run detailed hemodynamic simulations over large portions of the abdominal vasculature that include small branching vessels. Finally, novel <em>in vivo</em> photoacoustic approaches will be described for lipid imaging using endogenous contrast. This is of particular importance for vascular disease, including atherosclerosis, where lipid accumulation can influence plaque formation. The results from all of these studies suggest that differences in morphology, kinematics, hemodynamics, and composition play crucial roles in determining the evolution of both cardiac and vascular disease. <br/></p><span style="background-color: transparent;"><strong><em><br/></em></strong></span></div><div style="font-variant-numeric: normal; font-variant-east-asian: normal; background-color: transparent; border-width: 0px; font-family: "open sans", "helvetica neue", helvetica, arial, sans-serif; border-collapse: collapse; border-spacing: 0px;"><span style="background-color: transparent;"><br/></span></div><div style="font-variant-numeric: normal; font-variant-east-asian: normal; background-color: transparent; border-width: 0px; font-family: "open sans", "helvetica neue", helvetica, arial, sans-serif; border-collapse: collapse; border-spacing: 0px;"><span style="background-color: transparent;"><a href="https://bme.wustl.edu/bmeatwashu/Pages/seminar-series.aspx" style="background-color: #ffffff; text-decoration-line: underline; outline: 0px;">>> View all Biomedical Engineering seminars</a></span></div><p><br/></p>Lori Setton
CBAC Seminar: Richard W. Aldrich, Ph.D.https://engineering.wustl.edu/Events/Pages/CBAC-Seminar-Richard-Aldrich.aspx1770CBAC Seminar: Richard W. Aldrich, Ph.D.2018-11-19T06:00:00Z5:15 p.m.Brauer Hall, Room 12​<strong>Richard W. Aldrich, Ph.D. </strong><br/>Professor, Department of Neuroscience <br/>Karl Folkers Chair in Interdisciplinary  <br/>Biomedical Research II <br/>The University of Texas at Austin<div><span style="color: #666666; font-family: "open sans"; font-size: 1.15em; font-weight: 700;"><br/></span></div><div><span style="color: #666666; font-family: "open sans"; font-size: 1.15em; font-weight: 700;"></span><strong><a href="/Events/Documents/ALDRICH,%20RichardFLYER.pdf">Calcium, Calmodulin and Potassium Channels</a></strong><br/></div>Gwen Nguyen
No Classes (Thanksgiving Break)https://engineering.wustl.edu/Events/Pages/Thanksgiving-break-20018.aspx1589No Classes (Thanksgiving Break)2018-11-21T06:00:00Z
No Classes (Thanksgiving Break)https://engineering.wustl.edu/Events/Pages/Thanksgiving-break-2-20018.aspx1593No Classes (Thanksgiving Break)2018-11-22T06:00:00Z
No Classes (Thanksgiving Break)https://engineering.wustl.edu/Events/Pages/Thanksgiving-break-3-20018.aspx1594No Classes (Thanksgiving Break)2018-11-23T06:00:00Z
BME Seminar: Kausik Sihttps://engineering.wustl.edu/Events/Pages/BME-Seminar-Kausik-Si.aspx1610BME Seminar: Kausik Si2018-11-29T06:00:00Z10:10 a.m.Whitaker Hall Room 218<div style="font-variant-numeric: normal; font-variant-east-asian: normal; background-color: transparent; border-width: 0px; font-family: "open sans", "helvetica neue", helvetica, arial, sans-serif; border-collapse: collapse; border-spacing: 0px;"><span style="font-weight: 700;"><strong>Kausik Si, PhD</strong>, an Investigator at Stowers Institute for Medical Research and Professor in the Department of Molecular and Integrative Physiology at University of Kansas School of Medicine</span><span style="background-color: transparent;"><strong>, will present. </strong></span></div><div style="font-variant-numeric: normal; font-variant-east-asian: normal; background-color: transparent; border-width: 0px; font-family: "open sans", "helvetica neue", helvetica, arial, sans-serif; border-collapse: collapse; border-spacing: 0px;"><span style="background-color: transparent;"><br/></span></div><div style="font-variant-numeric: normal; font-variant-east-asian: normal; background-color: transparent; border-width: 0px; font-family: "open sans", "helvetica neue", helvetica, arial, sans-serif; border-collapse: collapse; border-spacing: 0px;"><span style="background-color: transparent;"><a href="https://bme.wustl.edu/bmeatwashu/Pages/seminar-series.aspx" style="background-color: #ffffff; outline: 0px;">>> View all Biomedical Engineering seminars</a></span></div>Rohit Pappu