https://engineering.wustl.edu/Profiles/Pages/Rohit-Pappu.aspx13Rohit Pappu<img alt="Rohit Pappu" src="/Profiles/PublishingImages/Pappu_Rohit_1_16_05.jpg?RenditionID=6" style="BORDER:0px solid;" />ProfessorRohit Pappu - Biomedical Engineering - Uncovers the biophysical principles of intrinsically disordered proteins & their connection to cellular processes<div>​​PhD, Tufts University, 1996</div><div>MS, Tufts University, 1993</div><div>BSc, Bangalore University, 1990</div><div> <br/> <p>  <a href="https://scholar.google.com/citations?user=VdzVqCwAAAAJ&hl=en&oi=ao"><img src="/Profiles/PublishingImages/gscholar.png" alt="" style="margin: 0px 0px -5px;"/> Google Scholar</a></p> </div>http://pappulab.wustl.edu/<p>​​Edwin H. Murty Professor of Engineering</p><h3>Research</h3><p>Rohit Pappu’s research interests are focused on intrinsically disordered proteins (IDPs), specifically their roles in transcriptional regulation, receptor mediated cell signaling, and cellular stress response. The Pappu lab has pioneered the combined use of polymer physics theories, novel homegrown computational methods, and experiments to probe the functional and phenotypic impacts of IDPs. Professor Pappu's lab also has a significant effort that is focused on neurodegeneration in Huntington’s and Alzheimer’s diseases. The central goal is to understand how protein aggregation and protein homeostasis pathways collude to give rise to neuronal death as a function of aging.​​<br/></p><h3>​Biography</h3><p>Professor Pappu joined Washington University in St. Louis in 2001. He received his PhD in biological physics from Tufts University and completed​ two biophysics postdoctoral fellowships at Washington University and Johns Hopkins University Schools of Medicine. Professor Pappu is the director of the <a href="http://cbse.wustl.edu/">Center for Biological Systems Engineering</a>, co-d​irector of the Center for High Performance Computing, and a member of the Hope Center for Neurological Disorders.</p><img alt="" src="/Profiles/ResearchImages/Pappu_Research.jpg?RenditionID=13" style="BORDER:0px solid;" /><p>​314-935-7958<br/><a href="mailto:pappu@wustl.edu">pappu@wustl.edu</a><br/>Brauer Hall, Room 2015a</p><a href="https://www.youtube.com/watch?v=_r6SGjn7PMo">play video</a>​ <ul><li><a href="/news/Pages/WashU-engineer-collaborators-win-1-million-international-grant-.aspx">WashU engineer, collaborators win $1 million international grant</a> <br/></li><li> <a href="/news/Pages/Pappu-Harmon-contribute-to-new-findings-on-cell-nucleolus-structure.aspx" style="background-color: #ffffff;">Pappu, Harmon contribute to new findings on cell nucleolus structure </a><br/></li><li> <a href="/news/Pages/Pappu-to-help-launch-Human-Dark-Proteome-Initiative.aspx" style="background-color: #ffffff;">Pappu to help launch Human Dark Proteome Initiative</a><br/></li><li> <a href="/news/Pages/WashU-engineers-help-unravel-molecular-control-of-hindering-cell-cycle.aspx" style="background-color: #ffffff;">How to stop dividing cancer cells in their tracks</a><br/></li><li> <a href="/news/Pages/Washington-University-expanding-supercomputer-with-NIH-grant.aspx" style="background-color: #ffffff;">Washington University expanding supercomputer with NIH grant</a><br/></li></ul>