Biomedical & Biological Imaging

This program seeks to bring the most innovative technology — whether it be next-generation hardware, multiple modalities, advanced image reconstruction or signal-processing methods, new contrast agents or novel applications — to bear on important basic science and clinical issues. Our goal is to develop new technologies to complement the already strong research and clinical imaging activities in our community.

Primary Faculty

• Hong Chen, assistant professor
• Song Hu, associate professor
• Abinav Jha, assistant professor
• Yoram Rudy, professor
• Jonathan Silva, assistant professor
• Michael Vahey, assistant professor
• Chao Zhou, associate professor
• Quing Zhu, professor

Affiliate Faculty 

Samuel Achilefu - Radiology

Molecular optical and multimodal imaging

Michael Altman - Radiation Oncology

Radiation therapy, High intensity focused ultrasound, MR-guided therapy, hyperthermia, brachytherapy

Hongyu An - Radiology

MRI, MR physics, sequence design, image reconstruction, PET/MR imaging, PET attenuation

Beau Ances, MD - Neurology

Alzheimer's disease, HIV

Kareem Azab - Radiation

Drug delivery, polymer conjugates, nanoparticles, lyposomes, targeted therapy, biodegradable polymeric emplants, medical devices, pharmaceutical sciences,

Martha Bagnall - Neuroscience

Vestibular and spinal neural circuits in zebrafish

Deanna Barch - Psychological & Brain Sciences

cognitive neuroscience, development, psychopathology, functional connectivity, structural connectivity, multi modal imaging

Randall Bateman - Neurology

Diagnostic clinical test biochemistry mass spectrometry process robotics Alzheimer's disease neurodegeneration

Adam Bauer - Radiology

Functional Optical Neuroimaging in Mice, Systems Neuroscience, Brain Network Connectivity, Neurovascular Coupling, Optogenetics, Stroke Recovery

Philip Bayly - Mechanical Engineering & Materials Science

biomechanics, mechanobiology, cell motility, flagella, cilia, imaging

Kevin Bennett - Radiology

Molecular imaging, kidney imaging, magnetic resonance, nanotechnology, physiology, renal disease, transplant

Mikhail Berezin - Radiology

Peripheral Nerves, Cancer Related Neuropathies, Imaging in Shortwave Infrared, Hyperspectral Imaging, Contrast Agents

Janine Bijsterbosch, MD, PhD - Radiology

Functional MRI; neuroimaging; functional connectivity; mental health; psychiatry; depression; anxiety; default mode network; trans-diagnostic; biomarker

Bruce Carlson - Neuroscience

Neurophysiology, sensory systems, behavior, evolution, mathematical modeling, neuroanatomy

Aadel Chaudhuri, MD - Radiation Oncology

liquid biopsy, cell-free DNA, early cancer detection, digital cytometry, translational genomics, computational biology

Shantanu Chakrabartty - Electrical & Systems Engineering

Self-powered sensors, wireless telemetry, energy harvesting, neuromorphic systems

Yao Chen - Neuroscience

Molecular dynamics, Neuromodulators, Sleep, Molecular sensors, Molecular actuators, Two photon Microscopy, Molecular systems, Signaling network, neuroscience, learning, Acetylcholine, Quantitative imaging, G protein coupled receptors, Fluorescence lifetime imaging microscopy, Engineering biosensors

Joseph Culver - Radiology

Diffuse optical tomography, non-invasive optical imaging

Li Ding, MD, PhD - Medicine

Cancer genomics, cancer proteomics, cancer evolution and progression, single cell and cellular imaging

Nico Dosenbach - Neurology

Precisions mapping of individual human brains; Real-time image processing

Adam Eggebrecht - Radiology

Optical Radiology, Diffuse Optics, Tomography, Modeling, Functional Near Infrared Spectroscopy, Analytical Methods, Photon Propagation, Finite Element, Autism, Child Development

James Fitzpatrick - Neuroscience

Cellular Imaging, Correlative Microscopy, X-Ray Nanotomography, Phase Contrast X-Ray Nanotomography, Focused Ion Beam Imaging, Cryo-Electron Microscopy, Single Particle Imaging, Cryo-Electron Tomography

Michael Gach - Radiation Oncology

MRI physics, quantitative imaging, quantitative hemodynamics, cancer, image processing, pulse sequences, real-time MRI

Guy Genin - Mechanical Engineering & Materials Science

Interfaces and adhesion in physiology and nature; optical strain analysis; continuum mechanics; viscoelasticity

Robert Gereau - Anesthesiology

Pain, optogenetics, optoelectronics, neural circuitry, in vivo imaging, electrophysiology

Michael Greenberg - Biochemistry & Molecular Biophysics

Heart failure, molecular motors, single molecule, optical trapping, stem cells, tissue engineering

Edward Han - Neuroscience

Two-photon calcium imaging, electrophysiology, virtual reality behavior, neuronal networks, learning and memory, hippocampus

Tim Holy - Neuroscience

Novel optical microscopy to record large neuronal populations

Geoff Hugo - Radiation Oncology

image guided radiation therapy, adaptive radiation therapy, machine learning, lung CT, image analysis

Daniel Kerschensteiner, MD - Ophthalmology & Visual Science

Neural circuits, vision, 2-photon imaging, electrophysiology, retina, visual processing

Vitaly Klyachko, PhD

Synaptic function and plasticity; neural circuits; information analysis; neurological disorders

Sándor Kovács, MD - Internal Medicine - Cardiovascular Division

mathematical physiology, kinematic modeling, cardiovascular biophysics, echocardiography, cardiac cathaterization, cardiac MRI, hemodynamics, human physiology

Alexxai Kravitz, MD, PhD

Striatum, dopamine, electrophysiology, open-source, devices, recording, electrodes, fiber optics, calcium imaging

Gregory Lanza, MD - Internal Medicine - Cardiovascular Division

Targeted drug delivery. Molecular imaging, Nanomedicine, Vascular disease, Liquid and Solid Cancer Technologiess, Contrast Agent Development

Eric Leuthardt, MD - Neurosurgery

Brain Computer Interfaces, Neuroprosthetics, Advanced Imaging, Resting State fMRI

Matthew Lew - Electrical & Systems Engineering

In-vivo imaging, 3D super-resolution microscopy, single-molecule fluorescence, computational optics

H. Harold Li - Radiology - Rad Sci

Radiation therapy dosimetry, Dose imaging device, Image-guided radiation therapy

Ilya Monosov - Neuroscience

Neuronal mechanisms of voluntary behavior

Josh Morgan - Ophthalmology

vision, retina, connectomics, synapse, imaging, electron microscopy, circuitry, thalamus, development, neuron, image analysis

Arye Nehorai - Electrical & Systems Engineering

Forward models, inverse models, statistical analysis, quantitative methods, modeling

Joseph O'Sullivan - Electrical & Systems Engineering

Computational imaging; imaging science; computed tomography; positron emission tomography; x-ray imaging

Ben Palanca, MD, PhD - Anesthesiology

Anesthesia, delirium, seizures, electroconvulsive therapy, depression, cardiac surgery, sleep, consciousness, cognition, electroencephalography, magnetic resonance imaging, clinical, cognitive dysfunction, perioperative monitoring, neuromodulation

Philip Payne - Internal Medicine

Translational Bioinformatics, Multi-Scale Modelling, Computational Drug Repositioning

Zachary Pincus - Gentetics

Systems Biology of Aging; Biology of Individuality

David Piston - Cell Biology & Physiology

Hormone secretion, signal transduction networks, proteinprotein interactions, fluorescence microscopy

Janice Robertson - Biochemistry and Molecular Biology

membrane protein folding thermodynamics assembly single-molecule TIRF microscopy computational modeling structure function oligomerization lipids

Erica Scheller - Internal Medicine - Bone & Mineral Diseases

Diabetes, fracture risk, advanced imaging, neurobiology, metabolic disease, bone regeneration, biosensors

Vijay Sharma - Radiology

Molecular Imaging, PET and SPECT Agents, Myocardial Perfusion, Alzheimer`s Disease, Multidrug Resistance

Kooresh Isaac Shoghi - Radiology - Rad Sci

Computational biology at the interface with in-vivo imaging in animal models, in particular as it relates to metabolic regulation and obesity, diabetes

Monica Shokeen - Radiology

Contrast Agent Development, Nanoparticles, Cancer Imaging, Cardiovascular Imaging, Functional PET, MRI

Lilianna Solnica-Krezel - Developmental Biology

Gastrulation, Regeneration, Development, Biology Embryogenesis, Convergence, Extension, Forward and Reverse Genetics, Zebrafish

Sheng-Kwei Victor Song - Radiology - Rad-Sci

Diffusion basis spectrum imaging, diffusion fMRI, inflammation, Cancer Technologies, axonal injury and loss, demyelination

Aristeidis Sotiras, PhD - Radiology

Machine learning; deep learning; image processing; image analysis; data science; neuroimaging; neurodegenerative diseases; neuropsychiatric disorders

S. Joshua Swamidass, MD - Pathology & Immunology

Machine learning, computational biology, chemical informatics, bioinformatics, neural networks, pharmacology, drug toxicity, drug design

Yuan-Chuan Tai - Radiology - Rad Sci

PET, molecular imaging, theranostic, radiotracer, plant imaging, phenotyping

Simon Tang - Orthopaedic Surgery

Disc Degeneration; Low back pain; osteoporosis and fragility

Daniel Thorek, PhD - Radiology

Molecular Imaging; Targeted Radiotherapy; Radiopharmaceuticals; Translational Drug Development

David Van Essen - Neuroscience

Functional brain-mapping

Yong Wang- Obstetrics & Gynecology

Diffusion MRI and PET imaging; Noninvasive Electrophysiology Imaging; Cancer and Immunotherapy Imaging; Preterm Birth; Alzheimer's disease

Pamela Woodard, MD - Radiology

PET, MRI, Molecular Imaging, Cardiac Imaging, Translational Research, PET tracers, Atherosclerosis

Deshan Yang - Radiation Oncology

Mohamed Zayed - Surgery

peripheral vascular disease, arteriovenous implants for treatment of diabetes, venous thrombectomy device treating DVT

Tiezhi Zhang - Radiation Oncology

Novel CT system, multi-pixel x-ray source, and radiation detector

Jie Zheng - Radiology

Cardiac MRI and PET, cardiovascular imaging, myocardial ischemia and heart failure, skeletal muscle exercise, diabetic foot

Tianyu Zhao, MD, PhD - Radiation Oncology

Proton Therapy, Adaptive Radiotherapy, Medical Imaging