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Orthopedic Engineering
Orthopedic Engineering combines principles of tissue engineering, cell biology, and biomechanics to generate new knowledge of bone and soft tissue biology and develop novel therapies to treat musculoskeletal disease.
This program seeks to understand the mechanical and material properties of bone and soft tissues (muscle, cartilage) and to exploit biomaterial and cellular processes to mediate injury responses and promote regeneration. Computational models play a significant role in the design of and development of new experimental methods and protocols.
Primary Faculty
- Lori Setton, chair and professor
- Nathaniel Huebsch, assistant professor
Affiliate Faculty

Guy Genin - Mechanical Engineering & Materials Science
Interfaces and adhesion in physiology and nature; optical strain analysis; continuum mechanics; viscoelasticity

Farshid Guilak - Orthopaedic Surgery
biomechanics, tissue engineering, regenerative medicine, osteoarthritis, synthetic biology, stem cells, mechanobiology, mechanotransduction, cell mechanics

Michael Harris - Physical Therapy
Whole Body & Joint-level Orthopaedic Biomechanics

Spencer Lake - Mechanical Engineering & Materials Science
Orthopedic, soft tissues, tendon/ligament, biomechanics, structure-function

Audrey McAlinden - Orthopaedic Surgery
cartilage engineering, chondrocytes, stem cells, osteoarthritis, microRNAs, long non-coding RNAs, growth factors

Gretchen Meyer - Physical Therapy
Skeletal Muscle Physiology, Adipose Signaling, Regeneration, Injury

W. Zachary Ray, MD - Neurosurgery
neuroprosthetics, resorbable electronics, nerve regeneration, spinal cord injury

Erica Scheller - Internal Medicine - Bone & Mineral Diseases
diabetes, fracture risk, advanced imaging, neurobiology, metabolic disease, bone regeneration, biosensors

Matthew Silva - Orthopaedic Surgery
Skeletal biomechanics and mechanobiology; bone strength; osteoporosis; skeletal imaging

Simon Tang - Orthopaedic Surgery
Disc Degeneration; Low back pain; osteoporosis and fragility